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Basic information

Basic information

English name: Hydroxyapatite；hydroxylapatite

For short: HAP

Physical and chemical properties:

Melting point: 1650°C

Specific gravity: 3.16g/cm3

Solubility: 0.4ppm

Ca/P: 1.67

Crystal structure: hexagonal crystal system (space group 176), monoclinic crystal system (space group 14)

Product specifications: powder, porous particles, block (non-standard) products

 

Introduction

HAP is the main inorganic component of human and animal bones. It can achieve chemical bonding with body tissues at the interface, it has a certain solubility in the body, can release harmless ions to the body, can participate in body metabolism, has a stimulating or inducing effect on bone hyperplasia, can promote the repair of defective tissues, and shows biological activity. Hydroxyapatite is the natural mineralization of calcium apatite (Ca5(PO4)3(OH)). However, it is often written in the form Ca10(PO4)6(OH)2 to highlight that it is composed of two parts: hydroxyl and apatite. The OH group can be replaced by fluoride, chloride and carbonate ions to form fluoro-apatite or chloro-apatite, where calcium ions can be replaced by various metal ions through ion exchange reactions to form the corresponding metal ion M apatite (M represents the metal ion that replaces calcium ions). Hydroxyapatite (HAP) is the main inorganic component of vertebrate bones and teeth, and the content of HAP is about 96 wt. %(92Vol.%) in human tooth enamel and about 69 wt. % in bone. Hydroxyapatite has excellent biocompatibility and bioactivity, and can be used as a bone or tooth induction factor, and has better remineralization and whitening effects on teeth in the field of oral health care. Experiments show that HAP particles have good biocompatibility and high affinity with tooth enamel, and its mineralized liquid can effectively form remineralization deposition, prevent the loss of calcium ions, solve the problem of enamel demineralization, and fundamentally prevent dental caries. The toothpaste containing HAP material has a strong adsorption effect on saliva protein and glucan, can reduce the dental plaque in the oral cavity of patients, promote the healing of gingivitis, and have a better prevention and treatment of dental caries and periodontal disease.

 

Functional effect

* Health brightening white

* Remove plaque

* Improve gum problems

* Prevent tooth decay

* Fresh breath

 

Properties and stability

Does not decompose if used and stored according to specifications, has no known dangerous reactions, and avoids oxides.

 

Scope of application

Bone replacement materials, plastic and cosmetic surgery, dental, chromatographic purification, calcium supplements are widely used in the manufacture of new materials that identify the composition of teeth or bones. In addition, hydroxyapatite is often used in bone tissue regeneration engineering because of its osteoinductive properties.