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According to reprints

It is reproduced Periplaneta americana is an insect class, has existed on the earth for hundreds of millions of years, and its contemporary dinosaurs have been extinct, but cockroach is still alive and thriving. Its ability to withstand radiation is more than ten times that of human beings, it can experience nuclear explosions and not die, and for a long time, whether people use physical and chemical agents to kill, the species is still not extinct, and its body must be different from other species of active substances, which has attracted the attention of scientists.

A long time ago, the people of Yunnan crushed the Periplaneta Americana and mixed it with herbs to treat injuries. The traditional Chinese medicine books such as Shennong Materia Medica and Compendium of Materia Medica also recorded the efficacy of the American cockroach, which can benefit qi and blood, and promote Yang and water.

Studies have found that there are more than 1,000 anti-cancer genes in the American cockroach, and explored its research and development possibilities in various fields such as anti-cancer, liver protection, allergy prevention, trauma repair, oral care, oral ulcer, and hair growth promotion.

Its extract, rich in epidermal growth factor, mucine, mucosine and other amino acids and small molecule active peptides and other active substances, has the following effects:

 

1. Wound repair

It plays an anti-infection and immunomodulatory role in all kinds of epidermal or mucous membrane injury. The healing new liquid produced by the alcohol extract of Periplaneta Americana was initially used to promote the growth of cell granulation in war, burn and trauma, and has a good effect. Can promote the healing of the wound, the healing principle is: Accelerate extracellular matrix synthesis and secretion; Cell function was activated after opening the macrophage channel; Accelerate the function of spontaneous and chemotactic movement of granulocytes, increase the number of granulocytes in the wound, strengthen the chemotactic function, and improve the phagocytosis ability. In dermatology began to treat trauma, pressure sores, later developed to internal medicine peptic ulcer, gastritis, esophagitis, etc., in pediatrics used to treat hand, foot and mouth disease, neonatal dermatitis, etc., stomatology applied to medical oral ulcer, periapical periodontitis, pharyngitis and so on. Clinical application shows that whether it is used alone or in combination, it has good efficacy and is more effective than antibiotics alone.Pharmacological studies have shown that as long as the extract contains Periplaneta Americana, it can accelerate the repair of damaged tissues and improve immunity.

 

2. Antitumor effect

Jiang Yongxin et al. demonstrated that the compound solution of Blattella Americana could induce BGC823 cells of gastric cancer, and the inhibition was time-dependent and concentration-dependent. Flow cytometry showed that BFC823 cells treated with the compound solution of Periplaneta Americana showed obvious apoptotic peak. With the extension of the treatment time, the apoptosis rate gradually increased, the cell cycle was blocked in G2/M phase, the number of cells in S phase was greatly reduced, and apoptosis and necrosis existed simultaneously in the whole process.

 

3. Clinical application

(1)Application in stomatology: Corresponding to oral aphthous ulcer, recurrent aphthous ulcer, stomatitis after radiotherapy and chemotherapy, oral ulcer, alveolar osteomyelitis, dry trough after extraction, wisdom tooth pericoronitis, periodontitis recovery after surgery.

 (2) Corresponding to radiation, chemotherapy, radiation microwave medicine caused by oral ulcer, radiation proctitis, bed sores, reduce the side effects of radiation, chemotherapy, microwave medicine, reduce skin injury after heat therapy, digestive system ulcer after rectal cancer.

 (3)Dermatology application: Corresponding to a variety of skin surface damage, skin cracking, neonatal diaper dermatitis, upper and lower limb wound infection, pressure sores, bedsores, all kinds of trauma after the treatment of external wounds.